Acute Care Nurse Practitioner Certification 2025 Practice Exam – The All-in-One Guide for Guaranteed Success!

Benzoyl peroxide and salicylic acid are considered comedolytic agents because they specifically target the development and presence of comedones, which are clogged hair follicles that contribute to acne formation. Comedolytic agents work by promoting the turnover of skin cells and preventing the blockage of pores. Benzoyl peroxide not only helps in reducing inflammation but also has antibacterial properties, while salicylic acid penetrates the pores to dissolve debris and dead skin cells.

In contrast, topical steroids primarily work by reducing inflammation and may not act directly on comedones. Antihistamines are typically used to manage allergic reactions and do not play a role in treating acne. Oral contraceptives can help regulate hormones that may contribute to acne but are not classified as comedolytic agents. Thus, benzoyl peroxide and salicylic acid are specifically recognized in dermatology for their efficacy in managing comedonal acne.